Osteoblast differentiation

Toll-like receptor-4-dependence of the lipopolysaccharide-mediated inhibition of osteoblast differentiation

Y. H. Liu, Huang, D., Li, Z. J., Li, X. H., Wang, X., Yang, H. P., Tian, S. P., Mao, Y., Liu, M. F., Wang, Y. F., Wu, Y., Han, X. F., Liu, Y. H., Huang, D., Li, Z. J., Li, X. H., Wang, X., Yang, H. P., Tian, S. P., Mao, Y., Liu, M. F., Wang, Y. F., Wu, Y., Han, X. F., Liu, Y. H., Huang, D., Li, Z. J., Li, X. H., Wang, X., Yang, H. P., Tian, S. P., Mao, Y., Liu, M. F., Wang, Y. F., Wu, Y., and Han, X. F., Toll-like receptor-4-dependence of the lipopolysaccharide-mediated inhibition of osteoblast differentiation, vol. 15, p. -, 2016.

Bone fractures or bones subjected to open conduction and internal fixation are easily infected by bacteria; bacterial lipopolysaccharide (LPS) has been recognized as an important pathogenic factor affecting bone fracture healing. Therefore, the effect of LPS on bone metabolism is relevant for bone healing. In this study, we investigated the effect of LPS on the expression of Toll-like receptor (TLR)-4 (an LPS receptor) by using real-time quantitative PCR and western blotting.

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