Osteoprotegerin

Opg/Rankl mRNA dynamic expression in the bone tissue of ovariectomized rats with osteoporosis

C. W. Li, Liang, B., Shi, X. L., and Wang, H., Opg/Rankl mRNA dynamic expression in the bone tissue of ovariectomized rats with osteoporosis, vol. 14, pp. 9215-9224, 2015.

We established animal models of osteoporosis in ovari­ectomized rats to detect osteoprogerin (Opg)/receptor activator of nuclear factor-κB ligand (Rankl) mRNA expression levels in the tib­ias and serum estradiol concentrations at different time points. Sixty Sprague-Dawley female rats were randomly selected and divided into an ovariectomized (OVX) group and sham-operated (SHAM) group. In the SHAM group, only a small amount of abdominal fat and tissues was removed from the rats.

Relationship between serum adiponectin and osteoprotegerin levels and coronary heart disease severity

H. L. Zhang and Jin, X., Relationship between serum adiponectin and osteoprotegerin levels and coronary heart disease severity, vol. 14, pp. 11023-11029, 2015.

This study aimed to explore serum adiponectin and osteoprotegerin levels in patients with coronary heart disease (CHD) and their correlation with inflammatory and ischemia factors. From September 2010 to Augest 2010, 347 CHD patients were enrolled for a retrospective analysis. Serum lipoprotein phospholipase A2 (Lp-PLA2), hypersensitive C-reactive protein (hs-CRP), ischemia modified albumin (IMA), and adiponectin and osteoprotegerin levels were detected and analyzed.

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