Analysis of polymorphisms in codons 11, 72 and 248 of TP53 in Brazilian women with breast cancer
“Analysis of polymorphisms in codons 11, 72 and 248 of TP53 in Brazilian women with breast cancer”, vol. 15, p. -, 2016.
, The association between TP53 gene polymorphisms and breast cancer (BC) in Brazilian women is a controversial topic. In this cross-sectional study, we evaluated the association between clinical pathological variables and three polymorphisms (TP53*11, TP53*72, and TP53*248) in BC patients and controls. Genomic DNA was extracted from the blood cells of 393 participants; the cancer-free control subjects were 26-72 years old (41 ± 11.03) and the BC patients were 28-80 years old (51 ± 10.70).