Selecting key genes associated with osteosarcoma based on a differential expression network
, “Selecting key genes associated with osteosarcoma based on a differential expression network”, vol. 14, pp. 17708-17717, 2015.
Despite recent advances in osteosarcoma diagnosis and therapy, much remains unclear about the molecular mechanisms involved in the disorder, and the discovery of novel drug-targeted genes is essential. We explored the potential molecular mechanisms and target genes involved in the development and progression of osteosarcoma. First, we identified the differentially expressed genes in osteosarcoma patients and matching normal controls. We then constructed a differential expression network based on differential and non-differential interactions.
