Percutaneous coronary intervention

Diversity of platelet function and genetic polymorphism in clopidogrel-treated Chinese patients

B. Sun, Li, J., Dong, M., Yang, L., Wu, C., Zhu, L., and Cong, Y. L., Diversity of platelet function and genetic polymorphism in clopidogrel-treated Chinese patients, vol. 14, pp. 1434-1442, 2015.

We investigated the correlation between genetic polymorphisms of cytochrome P450 enzyme genes and the outcome of clopidogrel treatment in 118 coronary disease patients after percutaneous coronary intervention at the Chinese PLA General Hospital. Patients were divided into an ischemia event relapse group (IERG) and a non-IERG group (NIERG) based on relapse of ischemia events within 6 months after percutaneous coronary intervention. Ischemia occurred in 26.27% of patients.

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