PGM1

Molecular characterization, expression patterns, and promoter activity analysis of PGM1 in pigs

J. Y. Yu, Shao, S. M., and Xiong, Y. Z., Molecular characterization, expression patterns, and promoter activity analysis of PGM1 in pigs, vol. 14, pp. 2816-2824, 2015.

The phosphoglucomutase 1 (PGM1) gene was differentially expressed in tissues of Chinese Meishan and Large White pigs. In this study, the promoter region, expression profile, and genetic mutations of the gene were determined. Expression of a 5'-deletion in both C2C12 and PK-15 cells showed that a negative regulatory element was at -1871 to +185 bp and a positive regulatory element was at -1158 to +185 bp. Among the different types of muscle fibers, PGM1 had the highest expression in both longissimus dorsi and biceps femoris.

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