A functional insertion/deletion polymorphism in the IL1A gene is associated with decreased risk of breast cancer
“A functional insertion/deletion polymorphism in the IL1A gene is associated with decreased risk of breast cancer”, vol. 15, p. -, 2016.
, The insertion/deletion polymorphism (rs3783553 TTCA/-) in the 3' untranslated region of interleukin-1A (IL1A) has been studied intensively and has been shown to affect tumor risk. We studied the frequency of the IL1A gene polymorphism rs3783553 and evaluated its relationship with breast cancer (BC). A hospital-based case-control study comprising 228 patients with histologically confirmed BC and 241 healthy subjects was conducted. Polymerase chain reaction was used to detect the IL1A rs3783553 polymorphism.