Polymorphism

Association between five common polymorphisms in microRNA genes and the risk of gastric cancer: a meta-analysis

Y. P. Gu, Yuan, Q. Y., Zhang, H., Wang, C. J., and Zhou, F., Association between five common polymorphisms in microRNA genes and the risk of gastric cancer: a meta-analysis, vol. 14, pp. 8375-8387, 2015.

Gastric cancer (GC) is a prevalent disease with a high mortality rate, especially in developing countries. Accumulating evidence suggests that single nucleotide polymorphisms in microRNA (miRNA) genes might influence the susceptibility to GC; such sequence variation might contribute to the development of disease by altering crucial cellular pathways. In this study, we assessed the correlation between the miR-146a G>C, miR-196a-2 C>T, miR-499 T>C, miRNA-27a A>G, and miRNA-149 T>C polymorphisms and the susceptibility to GC.

Subscribe to Polymorphism