Polymorphisms

Genetic polymorphisms of the folate pathway in amyotrophic lateral sclerosis and multiple sclerosis: a systematic review and meta-analysis

J. V. A. Neves, Lima, N. S., Costa, C. C. P., Santos, K. F., Reis, A. A. S., and Santos, R. S., “Genetic polymorphisms of the folate pathway in amyotrophic lateral sclerosis and multiple sclerosis: a systematic review and meta-analysis”, Genetics and Molecular Research, vol. 22, no. 1, 2023.

Lack of association of VEGF-A polymorphisms and susceptibility to amyotrophic lateral sclerosis and multiple sclerosis: A systematic review and meta-analysis

J. O. Costa, Costa, C. C. P., Lima, N. S., Santos, K. F., Reis, A. A. S., and Santos, R. S., “Lack of association of VEGF-A polymorphisms and susceptibility to amyotrophic lateral sclerosis and multiple sclerosis: A systematic review and meta-analysis”, Genetics and Molecular Research, vol. 22, no. 1, 2023.

Lack of significant association between MTHFR gene C677T polymorphism and colorectal cancer in the Azerbaijani population

H. Aslanov, Agaev, R., Bayramov, B., Hadizade, A., Alakbarova, N., Abdulrahimli, S., and Yagublu, V., “Lack of significant association between MTHFR gene C677T polymorphism and colorectal cancer in the Azerbaijani population”, Genetics and Molecular Reserach, vol. 1, no. 1, 2023.

Genetic epidemiology of Type 2 diabetes mellitus and complications in the Brazilian population

J. S. Campos, Santos, K. F., Costa, C. C. P., Barros, J. B. S., Gonçalves, V. S. S., Assunção, L. P., Reis, A. A. S., and Santos, R. S., “Genetic epidemiology of Type 2 diabetes mellitus and complications in the Brazilian population”, Genetics and Molecular Research, vol. 21, no. 1, 2022.

The IL18 rs1946518 and PTPN22 rs2476601 polymorphisms are not associated with adult- and childhood-onset type 1 diabetes mellitus

L. P. Campos, Graciolo, V., Welter, M., Lopes, M. S., Nesi-França, S., Picheth, G., and Rego, F. G. M., “The IL18 rs1946518 and PTPN22 rs2476601 polymorphisms are not associated with adult- and childhood-onset type 1 diabetes mellitus”, Genetics and Molecular Research, vol. 19, no. 4, 2020.

Evidence of association of glutathione-S-transferase GSTT1 and GSTM1 null genotypes with susceptibility to oral cancer based on meta-analysis

A. K. Lopes, Tacca, A. L. M., Nogueira, N. A., Sodario, J. A., Vilanova-Costa, C. A. S. T., Saddi, V. A., Filho, A. Vde Moraes, and Silva, A. M. T. C., “Evidence of association of glutathione-S-transferase GSTT1 and GSTM1 null genotypes with susceptibility to oral cancer based on meta-analysis”, Genetics and Molecular Research, vol. 19, no. 4, 2020.

Protein Z gene variants and risk of Idiopathic Recurrent Pregnancy Loss in Saudi Arabian women

W. Zammiti, Saidi, S., Shaman, A., and Duhier, F. Mohammed A., “Protein Z gene variants and risk of Idiopathic Recurrent Pregnancy Loss in Saudi Arabian women”, Genetics and molecular Research, vol. 16, no. 4, 2017.

rs3918242 MMP9 gene polymorphism is associated with myocardial infarction in Mexican patients

J. M. Rodríguez-Pérez, Vargas-Alarcón, G., Posadas-Sánchez, R., Zagal-Jiménez, T. X., Ortíz-Alarcón, R., Valente-Acosta, B., Tovilla-Zárate, C., Nostroza-Hernández, C., Pérez-Méndez, O., Pérez-Hernández, N., Rodríguez-Pérez, J. M., Vargas-Alarcón, G., Posadas-Sánchez, R., Zagal-Jiménez, T. X., Ortíz-Alarcón, R., Valente-Acosta, B., Tovilla-Zárate, C., Nostroza-Hernández, C., Pérez-Méndez, O., and Pérez-Hernández, N., “rs3918242 MMP9 gene polymorphism is associated with myocardial infarction in Mexican patients”, vol. 15, p. -, 2016.

Several studies have demonstrated that matrix metalloproteinases (MMPs) play a major role in atherosclerotic plaque disruption and lead to myocardial infarction (MI). We investigated the association between the MMP1 -1607 1G/2G (rs1799750), MMP3 -1612 5A/6A (rs3025058), and MMP9 -1562 C/T (rs3918242) polymorphisms and the risk of developing MI in a Mexican mestizo cohort.

Assessment of correlation between pre-miRNA-1757 polymorphism and chicken performance traits

H. Li, Jiang, K. R., Wang, S. H., Liu, X. J., Kang, X. T., Jiang, R. R., Li, Z. J., and Sun, G. R., “Assessment of correlation between pre-miRNA-1757 polymorphism and chicken performance traits”, vol. 14, pp. 12184-12195, 2015.

Single nucleotide polymorphism in microRNAs (miRNA) may influence their target gene selection and regulation efficiency, leading to animal phenotypic variation. The aim of this study was to evaluate the possible effect of single nucleotide polymorphisms in the miRNA-1757 gene precursor region (pre-mir-1757) on economic-related traits in chicken. Genotyping was performed using Sequenom MassArray® iPLEX GOLD System. Association analysis was performed using SPSS19.0.

An let-7 KRAS rs712 polymorphism increases hepatocellular carcinoma risk

D. Xiong, Song, Y. P., Xiong, W., and Liang, Y. D., “An let-7 KRAS rs712 polymorphism increases hepatocellular carcinoma risk”, vol. 14, pp. 14050-14055, 2015.

KRAS, also known as V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog, acts as an intracellular signal transducer. The oncogenic KRAS mutation is an essential step in the development of many types of human cancers, including hepatocellular carcinoma. Here we aimed to investigate the relationship between KRAS rs712 polymorphisms and hepatocellular carcinoma susceptibility. Five-hundred-and-fourteen participants were enrolled in a case-control study (262 cases and 252 normal subjects).

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