Prognosis

Investigation of the value of miR-21 in the diagnosis of early stage HCC and its prognosis: a meta-analysis

S. R. Yan, Liu, Z. J., Yu, S., and Bao, Y. X., Investigation of the value of miR-21 in the diagnosis of early stage HCC and its prognosis: a meta-analysis, vol. 14, pp. 11573-11586, 2015.

The diagnostic and prognostic value of miR-21 has been examined for hepatocellular carcinoma (HCC), with inconsistent results. Present meta-analysis summarized the diagnostic accuracy and the predictive role for survival of miR-21 in patients with HCC. All eligible studies were searched using PubMed, EMBASE, and Chinese National Knowledge Infrastructure (CNKI) databases up to October 2014. For the diagnostic meta-analysis, the indices of miR-21 in the diagnosis of HCC were pooled using bivariate random-effect approach models.

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