Prognostic factor

Overregulation of microRNA-212 in the poor prognosis of esophageal cancer patients

B. Qi, Liu, S. G., Qin, X. G., Yao, W. J., Lu, J. G., Guo, L., Wang, T. Y., Li, H. C., and Zhao, B. S., Overregulation of microRNA-212 in the poor prognosis of esophageal cancer patients, vol. 13, pp. 7800-7807, 2014.

There have been few reports evaluating the expression and function of the microRNA miR-212 in esophageal cancer. The aim of this study was to investigate the relationship between miR-212 expression and clinicopathological factors and prognoses of esophageal cancer. MicroRNA was extracted from 46 esophageal cancer patients using the Taqman MicroRNA assay. All patients were at the same tumor node metastasis stage, but with different prognoses, and had all undergone surgery.

Plasma human mammaglobin mRNA associated with poor outcome in patients with breast cancer

G. - W. Lee, Kim, J. - Y., Koh, E. - H., Kang, D., Choi, D. S., Maeng, K. - Y., and Lee, J. - S., Plasma human mammaglobin mRNA associated with poor outcome in patients with breast cancer, vol. 11, pp. 4034-4042, 2012.

Different treatment outcomes and prognoses in patients with breast cancer can be observed with similar clinical predictors; this is because the biology of breast cancer is complex and heterogenous, involving multiple unknown contributing factors. We looked for plasma human mammaglobin (hMAM) mRNA by RT-PCR in 82 Korean patients with breast cancer to determine if there is an association between the presence of plasma hMAM mRNA in these patients and known prognostic factors.

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