Prospective study

Prospective study of MTHFR genetic polymorphisms as a possible etiology of male infertility

S. - S. Li, Li, J., Xiao, Z., Ren, A. - G., and Jin, L., Prospective study of MTHFR genetic polymorphisms as a possible etiology of male infertility, vol. 13, pp. 6367-6374, 2014.

The aim of this study was to explore the relationship between 2 genetic polymorphisms of the methylenetetrahydrofolate reductase gene (MTHFR), C677T and A1298C, and determine the long-term reproductive outcome in infertile men. This was a prospective study conducted in an andrology clinic. Men with a 1-year history of infertility were assessed for the MTHFR polymorphisms at a 5-year follow-up.

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