Prostate cancer

Polymorphisms of eNOS, catalase, and myeloperoxidase genes in prostate cancer in Turkish men: preliminary results

G. G. Ceylan, Ceylan, C., Gülmemmedov, B., Tonyalı, Ş., Odabaş, O., Gözalan, A., Keleş, İ., Ozturk, E., Ceylan, G. G., Ceylan, C., Gülmemmedov, B., Tonyalı, Ş., Odabaş, O., Gözalan, A., Keleş, İ., and Ozturk, E., Polymorphisms of eNOS, catalase, and myeloperoxidase genes in prostate cancer in Turkish men: preliminary results, vol. 15, p. -, 2016.

Prostate cancer (PCa) is the most common type of neoplasm in European males. Genetic and epigenetic factors contribute to PCa development and progression. In this study, we aimed to assess the relationship between PCa and polymorphisms in the genes encoding endothelial nitric oxide synthase (eNOS), catalase (CAT), and myeloperoxidase (MPO). In total, 193 patients were included in the study. Patients were divided into three groups: PCa (78), benign prostate hyperplasia (40), and control males (75).

Interleukin-6 -572G/C polymorphism and prostate cancer susceptibility

W. J. Huang, Wu, L. J., Min, Z. C., Xu, L. T., Guo, C. M., Chen, Z. P., Lou, X. J., Xu, B., Lv, B. D., Huang, W. J., Wu, L. J., Min, Z. C., Xu, L. T., Guo, C. M., Chen, Z. P., Lou, X. J., Xu, B., and Lv, B. D., Interleukin-6 -572G/C polymorphism and prostate cancer susceptibility, vol. 15, p. -, 2016.

Strong evidence suggests that cancer-associated inflammation promotes tumor growth and progression, and interleukin-6 (IL6) is an important modulator of inflammation. However, the roles of IL6 and mutations of its corresponding gene in prostate cancer have not been clearly documented. We retrieved data from the Oncomine database concerning IL6 expression in prostate cancer and its role in prostate-specific antigen (PSA) recurrence.

Subscribe to Prostate cancer