QTL

Genetic and molecular mechanisms of aluminum tolerance in plants

C. C. Simões, Melo, J. O., Magalhães, J. V., and Guimarães, C. T., Genetic and molecular mechanisms of aluminum tolerance in plants, vol. 11. pp. 1949-1957, 2012.

Aluminum (Al) toxicity restricts root growth and agricultural yield in acid soils, which constitute approximately 40% of the potentially arable lands worldwide. The two main mechanisms of Al tolerance in plants are internal detoxification of Al and its exclusion from root cells.

Bulked segregant analysis for relative water content to detect quantitative trait loci in wheat under drought stress

M. R. Naroui Rad, M. Kadir, A., Rafii, M. Y., Jaafar, H. Z. E., and Naghavi, M. R., Bulked segregant analysis for relative water content to detect quantitative trait loci in wheat under drought stress, vol. 11, pp. 3882-3888, 2012.

This study was carried out to evaluate the genetic effect of quantitative trait loci (QTLs) conferring drought tolerance in wheat. A population of 120 F2 individuals from the cross between the drought-tolerant S-78-11 and drought-sensitive Tajan cultivars were analyzed for their segregation under drought stress conditions. The relative water content under drought stress conditions exhibited continuous variation, indicating the minor gene effects on the trait. Single-marker analysis (SMA) was carried out to detect the main QTL association with drought tolerance.

Polymorphisms in FGFBP1 and FGFBP2 genes associated with carcass and meat quality traits in chickens

A. M. Felício, Boschiero, C., Balieiro, J. C. C., Ledur, M. C., Ferraz, J. B. S., Moura, A. S. A. M. T., and Coutinho, L. L., Polymorphisms in FGFBP1 and FGFBP2 genes associated with carcass and meat quality traits in chickens, vol. 12, pp. 208-222, 2013.

In the past, the focus of broiler breeding programs on yield and carcass traits improvement led to problems related to meat quality. Awareness of public concern for quality resulted in inclusion of meat quality traits in the evaluation process. Nevertheless, few genes associated with meat quality attributes are known. Previous studies mapped quantitative trait loci for weight at 35 and 42 days in a region of GGA4 flanked by the microsatellite markers, MCW0240 and LEI0063.

Genetic analysis of agronomic traits associated with plant architecture by QTL mapping in maize

Z. P. Zheng and Liu, X. H., Genetic analysis of agronomic traits associated with plant architecture by QTL mapping in maize, vol. 12, pp. 1243-1253, 2013.

Maize (Zea mays L.) is one of the most important cereal crops worldwide, and increasing the grain yield and biomass has been among the most important goals of maize production. The plant architecture can determine the grain yield and biomass to some extent; however, the genetic basis of the link between the plant architecture and grain yield/biomass is unclear.

Major quality trait analysis and QTL detection in hexaploid wheat in humid rain-fed agriculture

H. M. Li, Tang, Z. X., Zhang, H. Q., Yan, B. J., and Ren, Z. L., Major quality trait analysis and QTL detection in hexaploid wheat in humid rain-fed agriculture, vol. 12, pp. 1740-1751, 2013.

Humid rain-fed agriculture is a special environment for wheat (Triticum aestivum) culture that tends to negatively affect wheat yield and quality. To identify quality characters of wheat in a humid environment, we conducted quality analysis and quantitative trait loci (QTL) detection in a recombinant inbred line whose parent had a high level of quality for several years. We found that high-quality wheat had less gluten content and lower protein content. Apparently, wheat quality and associated quantity traits were in a dynamic state of equilibrium.

QTL identification of ear leaf morphometric traits under different nitrogen regimes in maize

Z. P. Zheng and Liu, X. H., QTL identification of ear leaf morphometric traits under different nitrogen regimes in maize, vol. 12, pp. 4342-4351, 2013.

The ear leaf is one of the most important leaves in maize (Zea mays); it affects plant morphology and yield. To better understand its genetic basis, we examined ear leaf length, ear leaf width, and ear leaf area for quantitative trait locus (QTL) mapping in a recombinant inbred line population under two nitrogen regimes. Nine QTLs, on chromosomes 1 (one), 2 (one), 3 (one), 4 (three), 7 (one), and 8 (two), were mapped under the high nitrogen regime, which explained phenotypic variation ranging from 5.4 to 14.8%.

Critical evaluation of transcription factor Atf2 as a candidate modulator of alcohol preference in mouse and human populations

L. S. Wang, Jiao, Y., Huang, Y., Liu, X. Y., Gibson, G., Bennett, B., Hamre, K. M., Li, D. W., Zhao, H. Y., Gelernter, J., Kranzler, H. R., Farrer, L. A., Lu, L., Wang, Y. J., and Gu, W. K., Critical evaluation of transcription factor Atf2 as a candidate modulator of alcohol preference in mouse and human populations, vol. 12, pp. 5992-6005, 2013.

In prior work, congenic strains carrying the DBA/2Igb (D2) region of chromosome 2 (Chr2) for alcohol preference were bred onto a C57BL/6Ibg (B6) background and as predicted were found to reduce voluntary consumption. Subsequently, interval-specific congenic recombinant strains (ISCRS) were generated and also tested. These ISCRS strains reduced the quantitative trait loci (QTL) interval to a comparatively small 3.4 Mb region. Here, we have exploited an integrative approach using both murine and human populations to critically evaluate candidate genes within this region.

Identification and validation of a new grain weight QTL in rice

J. M. Bian, He, H. H., Li, C. J., Shi, H., Zhu, C. L., Peng, X. S., Fu, J. R., He, X. P., Chen, X. R., Hu, L. F., and Ouyang, L. J., Identification and validation of a new grain weight QTL in rice, vol. 12, pp. 5623-5633, 2013.

The genetic control of grain weight (GW) remains poorly understood. Quantitative trait loci (QTLs) determining the GW of rice were identified using a natural GW mutant, sgw. Using a segregating population derived from sgw (low GW) and cultivar 9311 ('9311'; indica, high GW), the chromosome segment associated with GW was detected on the short arm of chromosome 7.

Evaluation of TFAM and FABP4 gene polymorphisms in three lines of Nellore cattle selected for growth

D. R. Ayres, Souza, F. R. P., Mercadante, M. E. Z., Fonseca, L. F. S., Tonhati, H., Cyrillo, J. N. S. G., Bonilha, S. F. M., and Albuquerque, L. G., Evaluation of TFAM and FABP4 gene polymorphisms in three lines of Nellore cattle selected for growth, vol. 9, pp. 2050-2059, 2010.

We analyzed the polymorphisms TFAM HaeIII, TFAM MboI and FABP4 MspA1I in three Nellore lines selected for growth in order to evaluate how selection affects the frequencies of these polymorphisms and evaluate their association with growth and carcass traits in Zebu cattle. Birth, weaning and yearling weights, rump height, longissimus muscle area, backfat thickness, and rump fat thickness were analyzed.

Polymorphisms associated with egg number at 300 days of age in chickens

H. P. Xu, Zeng, H., Zhang, D. X., Jia, X. L., Luo, C. L., Fang, M. X., Nie, Q. H., and Zhang, X. Q., Polymorphisms associated with egg number at 300 days of age in chickens, vol. 10, pp. 2279-2289, 2011.

We looked for variations that could be associated with chicken egg number at 300 days of age (EN300) in seven genes of the hypothalamic-pituitary-gonadal axis, including gonadotrophin-releasing hormone-I (GnRH-I), GnRH receptor (GnRHR), neuropeptide Y (NPY), dopamine D2 receptor (DRD2), vasoactive intestinal polypeptide (VIP), VIP receptor-1 (VIPR-1), prolactin (PRL), and the QTL region between 87 and 105 cM of the Z chromosome.

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