Quality of life

Clinical characteristics of men with non-mosaic Klinefelter syndrome in northeastern China: implications for genetic counseling

M. Zhang, Fan, H. - T., Zheng, H. - S., Zhang, Q. - S., Feng, S. - Q., and Li, R. - W., Clinical characteristics of men with non-mosaic Klinefelter syndrome in northeastern China: implications for genetic counseling, vol. 14, pp. 10897-10904, 2015.

Klinefelter syndrome (KS) is the most common genetic cause of male infertility. Widespread development in assisted reproductive technology has provided non-mosaic KS patients with the opportunity of having biological children. Testosterone replacement therapy and micro-dissection testicular sperm extraction are effective sperm retrieval techniques for KS patients. Despite the success of sperm retrieval and intracytoplasmic sperm injection (ICSI), some areas of early aggressive hormonal spermatogenesis and appropriate management of KS remain controversial.

Subscribe to Quality of life