Quantitative fluorescence polymerase chain reaction

Genetic analysis of STR markers on chromosome 21 in a Han population from southeast China

Y. N. Zhu, Lu, S. M., Wang, M., Shen, F. X., Chen, Y., and Hu, J. J., Genetic analysis of STR markers on chromosome 21 in a Han population from southeast China, vol. 14, pp. 1718-1725, 2015.

Short tandem repeats (STRs) are highly polymorphic sequences and have been extensively used as genetic markers in mapping studies, disease diagnosis, and human identity testing. In this study, 11 STR markers on chromosome 21, including D21S1432, D21S11, D21S1246, D21S1412, D21S1437, D21S1442, D21S2039, D21S1270, D21S1435, D21S1409, and D21S1446, were analyzed in 740 unrelated Han individuals from southeast China. A total of 132 alleles, ranging from 7-21 for each locus, were named according to the guidelines of the International Society for Forensic Haemogenetics.

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