RAP1GAP

Expression of Rap1GAP in human myeloid disease following microarray selection

X. Qi, Chen, Z., Qian, J., Cen, J., and Gu, M., Expression of Rap1GAP in human myeloid disease following microarray selection, vol. 7, pp. 379-387, 2008.

To find the underlying causes of primary myelodysplastic syndrome (MDS), the gene expression profiling of both CD34+ cells and bone marrow mononuclear cells from MDS patients was performed using oligonucleotide microarray and cDNA microarrays, respectively. Several candidate genes which were differentially expressed in MDS patients versus normal controls were selected and confirmed in expanding samples by quantitative real-time reverse transcription-polymerase chain reaction after clustering and bioinformatics analysis.

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