Regulatory T cells

Correlation of CD4+ CD25+ Foxp3+ Treg with the recovery of joint function after total knee replacement in rats with osteoarthritis

S. - Y. Guo, Ding, Y. - J., Li, L., Zhang, T., Zhang, Z. - Z., and Zhang, E. - S., Correlation of CD4+ CD25+ Foxp3+ Treg with the recovery of joint function after total knee replacement in rats with osteoarthritis, vol. 14, pp. 7290-7296, 2015.

In this study, we observed changes in CD4+ CD25+ Foxp3+ Treg expression in rats with osteoarthritis (OA) to explore the role that CD4+ CD25+ Foxp3+ Treg plays in the decline in the condition of OA rats. Thirty rats were randomly divided into 2 groups equally and OA was induced in rats in the model group by injection of papain and l-cysteine into the right knee joint.

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