Reoxygenation

Protective effects against and potential mechanisms underlying the effect of magnesium isoglycyrrhizinate in hypoxiareoxygenation injury in rat liver cells

J. Zheng, Wu, G., Hu, G. X., Peng, Y. Z., and Xiong, X. J., Protective effects against and potential mechanisms underlying the effect of magnesium isoglycyrrhizinate in hypoxiareoxygenation injury in rat liver cells, vol. 14, pp. 15453-15461, 2015.

We examined the protective effects of magnesium isoglycyrrhizinate (MgIG) on hypoxia-reoxygenation injury in rat liver cells. Rat liver cells in the logarithmic growth phase were divided into the hypoxia-reoxygenation injury model group and MgIG pretreatment group (0.01, 0.1, 1, 10, 100 mg/mL). After 24-h pretreatment, we detected the effects of MgIG on liver cell viability using the methyl thiazolyl tetrazolium (MTT) assay at 6-h hypoxia and 4-h reoxygenation.

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