Retina

Expression of a novel splicing variant of Pcp2 in closely related laboratory rodents

M. A. Przybyła, Nowacka-Chmielewska, M. M., Barski, J. J., Przybyła, M. A., Nowacka-Chmielewska, M. M., and Barski, J. J., Expression of a novel splicing variant of Pcp2 in closely related laboratory rodents, vol. 15, p. -, 2016.

Purkinje cell protein-2 (PCP2), also known as L7, is a member of the GoLoco protein family with highly cell-specific expression, being restricted to cerebellar Purkinje cells and retinal bipolar neurons in various species. However, its function in these tissues is unknown. Previous studies have suggested that PCP2 is a guanine nucleotide dissociation inhibitor, or a guanine nucleotide exchange factor. The Pcp2 gene is known to have many splice variants in both cerebellar Purkinje cells and retinal bipolar neurons.

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