rs16998248

Effect of ZNF217 gene polymorphisms on colorectal cancer development in a Mexican population

R. Ramírez-Ramírez, Gutierrez-Angulo, M., Magaña, M. T., Moreno-Ortiz, J. M., Partida-Pérez, M., Muñiz-Mendoza, R., Peregrina-Sandoval, J., Suárez-Villanueva, A. S., Centeno-Flores, M., Maciel-Gutiérrez, V. M., Cabrales-Vazquez, E., and Ayala-Madrigal, M. L., “Effect of ZNF217 gene polymorphisms on colorectal cancer development in a Mexican population”, vol. 14, pp. 362-367, 2015.

The ZNF217 gene, a potential oncogene amplified and overexpressed in several cancers including colorectal cancer (CRC), acts as a transcription factor that activates or represses target genes. The polymorphisms rs16998248 (T>A) and rs35720349 (C>T) in coronary artery disease have been associated with reduced expression of ZNF217. In this study, we analyzed the 2 polymorphisms in Mexican patients with CRC.

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