RT-PCR

Expression profile of the GA733 gene family in colorectal cancer: correlation with clinicopathological parameters

I. Mamaloudis, Zacharoulis, D., Samara, M., Papadopoulos, G., Samara, S., Koukoulis, G., Chatzitheofilou, C., and Kollia, P., Expression profile of the GA733 gene family in colorectal cancer: correlation with clinicopathological parameters, vol. 14, pp. 14772-14781, 2015.

GA733-1/-2/-3 genes have been detected in various types of cancer, although their role has not been fully clarified. GA733-2 and GA733-1 have been correlated with lymph node metastases in laryngeal cancer and liver metastases, respectively. Only a few studies have elucidated the mechanisms regulating GA733-1/-2 expression and their effect on colorectal cancer. Therefore, the expression pattern and the role of the aforementioned molecules in colorectal carcinogenesis were evaluated in this study.

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