Sacral nerve stimulation

Effects of sacral nerve stimulation with acupuncture on gut transit time and c-kit expression in colon of rats with slow transit constipation

Y. G. Zhang, Shao, W. J., Gu, Y. F., Qiu, J. F., Yuan, L., Li, G. D., Zhang, Y. G., Shao, W. J., Gu, Y. F., Qiu, J. F., Yuan, L., and Li, G. D., Effects of sacral nerve stimulation with acupuncture on gut transit time and c-kit expression in colon of rats with slow transit constipation, vol. 15, p. -, 2016.

Sacral nerve stimulation (SNS) is an alternative surgical approach to alleviate fecal incontinence and constipation. This study aimed to explore the effects and underlying mechanisms of SNS with acupuncture on gut transit time and colon c-kit protein expression in rats with slow transit constipation (STC). Fifty Sprague-Dawley rats were randomly divided into five groups: blank control, SNS, Mosapride, sham SNS, and STC model control group. The STC model was established by subcutaneous injection of morphine. Each group was treated over a 15-day period.

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