SELEX

Screening and identification of the nucleic acid aptamers in nasopharyngeal carcinoma

W. - X. Chen, Zhang, K. - H., Zou, X. - S., Chen, Y. - Q., and Li, J. - G., Screening and identification of the nucleic acid aptamers in nasopharyngeal carcinoma, vol. 12, pp. 6850-6857, 2013.

To screen the nucleic acid aptamers of the EB virus-positive nasopharyngeal carcinoma cells, we used SELEX technology and synthesized in vitro a 78-nucleotide random DNA library. We used normal nasopharyngeal epithelial cells and EB virus-positive low differentiated nasopharyngeal carcinoma cells as target to conduct 10 cycles of screening, cloning, sequencing, and identification of the aptamers.

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