Sepsis

Protective effect and mechanism of hydrogen treatment on lung epithelial barrier dysfunction in rats with sepsis

L. - D. Liu, Wu, X. - Y., Tao, B. - D., Wang, N., Zhang, J., Liu, L. - D., Wu, X. - Y., Tao, B. - D., Wang, N., Zhang, J., Liu, L. - D., Wu, X. - Y., Tao, B. - D., Wang, N., and Zhang, J., “Protective effect and mechanism of hydrogen treatment on lung epithelial barrier dysfunction in rats with sepsis”, vol. 15, p. -, 2016.

This study aimed to explore the protective effect of hydrogen and to investigate the underlying mechanism of its preliminary effect on the alveolar epithelial barrier function in septic rats. Forty-five male Sprague-Dawley rats were divided randomly into three groups (N = 15): control [saline injection (intraperitoneal, ip), air drawing; SA], acute lung injury group [lipopolysaccharide (LPS) injection (ip, 15 mg/kg), air drawing; LA], and acute lung injury combined with hydrogen drawing group [LPS injection (ip, 15 mg/kg), 2% hydrogen drawing; LH].

An outbreak of Candida parapsilosis fungemia among preterm infants

W. Guo, Gu, H. F., Zhang, H. G., Chen, S. B., Wang, J. Q., Geng, S. X., Li, L., Liu, P., Liu, X., Ji, Y. R., Li, S. W., and Yang, L., “An outbreak of Candida parapsilosis fungemia among preterm infants”, vol. 14, pp. 18259-18267, 2015.

In this article, we describe the first outbreak of Candida parapsilosis fungemia in our hospital. We examined a cluster of four nosocomial cases of C. parapsilosis fungemia that occurred in the neonatal intensive care unit (NICU) of the Affiliated Xingtai People’s Hospital of Hebei Medical University over a two-week period. We ascertained patient parameters including clinical characteristics, blood and sputum cultures, and drug sensitivity test results.

Association between PAI-1 polymorphisms and plasma PAI-1 level with sepsis in severely burned patients

Y. F. Chi, Chai, J. K., Yu, Y. M., Luo, H. M., Zhang, Q. X., and Feng, R., “Association between PAI-1 polymorphisms and plasma PAI-1 level with sepsis in severely burned patients”, vol. 14, pp. 10081-10086, 2015.

We investigated the association between plasminogen activator inhibitor-1 (PAI-1) polymorphisms and plasma PAI-1 level with sepsis in severely burned patients. A total of 182 patients with burn areas lager than 30% of the body surface area were enrolled in this study. Peripheral blood samples were obtained from 103 patients with sepsis (sepsis group) and 79 patients without sepsis (control group). An allele-specific polymerase chain reaction assay was used to determine PAI-1 polymorphism 4G/5G distribution.

Subscribe to Sepsis