Serum

Serum miR-200c expression level as a prognostic biomarker for gastric cancer

H. - P. Zhang, Sun, F. - B., and Li, S. - J., Serum miR-200c expression level as a prognostic biomarker for gastric cancer, vol. 14, pp. 15913-15920, 2015.

The aim of the present study was to analyze the serum expression level of microRNA-200c (miR-200c) in gastric cancer (GC) patients and to determine the relationship between this expression and clinicopathological features and survival. Serum samples were obtained from 98 patients with GC between February 2008 and January 2013. Quantitative RT-PCR was used to assess miR-200c expression levels in serum samples. Survival curves were plotted using the Kaplan-Meier method, and differences between survival curves were compared by the log rank test.

Downregulation of serum DKK-1 predicts poor prognosis in patients with papillary thyroid cancer

Y. P. Zhao, Wang, W., Wang, X. H., Xu, Y., Wang, Y., Dong, Z. F., and Zhang, J. J., Downregulation of serum DKK-1 predicts poor prognosis in patients with papillary thyroid cancer, vol. 14, pp. 18886-18894, 2015.

The Wnt inhibitor dickkopf-1 (DKK-1) has been shown to be closely correlated with tumor initiation and progression in various types of cancers. However, the serum level of DKK-1 in patients with papillary thyroid cancer (PTC) and its potential clinical significance is poorly understood. Enzyme-linked immunosorbent assay (ELISA) was used to evaluate the level of serum DKK-1 in patients with PTC (N = 132) and healthy controls (N = 40).

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