Low levels of serum miR-99a is a predictor of poor prognosis in breast cancer
“Low levels of serum miR-99a is a predictor of poor prognosis in breast cancer”, vol. 15, p. -, 2016.
, MicroRNA (miRNA) deregulation has been previously linked to the initiation and development of breast cancer. Although miR-99a is aberrantly expressed in many types of cancers, including breast cancer, the serum miR-99a expression level in breast cancer and its clinical significance remains unknown. Blood samples were obtained from 72 patients with breast cancer and 40 healthy volunteers, and subjected to real-time polymerase chain reaction to evaluate the level of expression of serum miR-99a in the study participants.