Sichuan snub-nosed monkey

Uneven evolutionary rate of the melatonin-related receptor gene (GPR50) in primates

Y. Zhang, Li, H. Q., Yao, Y. F., Liu, W., Ni, Q. Y., Zhang, M. W., and Xu, H. L., Uneven evolutionary rate of the melatonin-related receptor gene (GPR50) in primates, vol. 14, pp. 680-690, 2015.

The melatonin-related receptor GPR50 plays an important role in mammalian adaptive thermogenesis in response to calorie intake. The evolutionary history of the GPR50 gene is poorly understood in primates; however, it has been reported that GPR50 is the mammalian ortholog of Mel1c, which has been well characterized.

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