Signaling pathways

Inhibition of adipogenic differentiation of bone marrow mesenchymal stem cells by erythropoietin via activating ERK and P38 MAPK

G. X. Liu, Zhu, J. C., Chen, X. Y., Zhu, A. Z., Liu, C. C., Lai, Q., and Chen, S. T., Inhibition of adipogenic differentiation of bone marrow mesenchymal stem cells by erythropoietin via activating ERK and P38 MAPK, vol. 14, pp. 6968-6977, 2015.

We examined whether erythropoietin (EPO) can inhibit adipogenic differentiation of mesenchymal stem cells (MSCs) in the mouse bone marrow and its underlying mechanism. We separated and extracted mouse bone marrow MSCs and induced adipogenic differen­tiation using 3-isobutyl-1-methylxanthine, insulin, and dexamethasone. Different concentrations of EPO were added to the cells and observed by Oil Red O staining on the 20th day to quantitatively analyze the degree of cell differentiation.

Cell signaling pathways in Paracoccidioides brasiliensis - inferred from comparisons with other fungi

L. Fernandes, Araújo, M. A. M., Amaral, A., Reis, V. Castelo Br, Martins, N. F., and Felipe, M. S., Cell signaling pathways in Paracoccidioides brasiliensis - inferred from comparisons with other fungi, vol. 4, pp. 216-231, 2005.

The human fungal pathogen Paracoccidioides brasiliensis is an ascomycete that displays a temperature-dependent dimorphic transition, appearing as a mycelium at 22°C and as a yeast at 37°C, this latter being the virulent form. We report on the in silico search made of the P.

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