Silent information regulator 5

Polymorphisms in the SIRT5 gene and their association with body measurement and ultrasound traits in Qinchuan cattle

L. S. Gui, Wang, H. C., Liu, G. Y., and Zan, L. S., Polymorphisms in the SIRT5 gene and their association with body measurement and ultrasound traits in Qinchuan cattle, vol. 14, pp. 3843-3853, 2015.

Silent information regulator 5 (SIRT5), a member of the Sirtuin family class III nicotinamide adenine dinucleotide-dependent protein deacetylases, plays an important role in metabolic and aging processes in mammals. We identified 4 single-nucleotide polymorphisms (SNPs) (G22010A, G22052A, G22119T, and G22245C) in the 3' untranslated regions of the SIRT5 gene from 572 Qinchuan cattle by sequencing and investigating their association with growth and ultrasound traits. The frequencies of genotype GG and allele G were high at the 4 SNPs.

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