Single nucleotide polymorphism

Association between miR-137 polymorphism and risk of schizophrenia: a meta-analysis

M. L. Ou, Liu, G., Xiao, D., Zhang, B. H., Guo, C. C., Ye, X. G., Liu, Y., Zhang, N., Wang, M., Han, Y. J., Ye, X. H., Jing, C. X., Yang, G., Ou, M. L., Liu, G., Xiao, D., Zhang, B. H., Guo, C. C., Ye, X. G., Liu, Y., Zhang, N., Wang, M., Han, Y. J., Ye, X. H., Jing, C. X., and Yang, G., Association between miR-137 polymorphism and risk of schizophrenia: a meta-analysis, vol. 15, p. -, 2016.

miR-137, a brain-enriched microRNA, is involved in the control of neuronal proliferation, differentiation, and dendritic arborization, all of which are important for proper neurogenesis and relevant to schizophrenia. miR-137 is also known to regulate many genes implicated in schizophrenia risk. Although reports have associated the miR-137 polymorphism rs1625579 with this disease, their results have been inconsistent. The aim of this meta-analysis was to evaluate the relationship between rs1625579 and schizophrenia.

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