Single nucleotide polymorphism

Association between the rs189037 single nucleotide polymorphism in the ATM gene promoter and cognitive impairment

X. Ding, Yue, J. R., Yang, M., Hao, Q. K., Xiao, H. Y., Chen, T., Gao, L. Y., and Dong, B. R., Association between the rs189037 single nucleotide polymorphism in the ATM gene promoter and cognitive impairment, vol. 14, pp. 4584-4592, 2015.

The aim of this study was to explore the existence of a relationship between the rs189037 single nucleotide polymorphism (SNP) of the ataxia telangiectasia mutated (ATM) gene and cognitive impairment in the elderly (aged 60 years and above). In a cohort, 505 residents of Suinung City were consecutively recruited and their cognitive function was measured using a 30-point Mini-Mental State Examination (MMSE). The subjects were divided into cognitive impairment group and control group on the basis of MMSE scores.

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