Single nucleotide polymorphisms

Association between interleukin-17A polymorphism and coronary artery disease susceptibility in the Chinese Han population

G. B. Su, Guo, X. L., Liu, X. C., Cui, Q. T., Zhou, C. Y., Su, G. B., Guo, X. L., Liu, X. C., Cui, Q. T., and Zhou, C. Y., Association between interleukin-17A polymorphism and coronary artery disease susceptibility in the Chinese Han population, vol. 15, p. -, 2016.

Coronary artery disease (CAD) is a major global health problem. In China, the incidence of CAD and the rate of mortality arising from it have increased every year. Interleukin-17A (IL-17A) is a proinflammatory cytokine produced by activated T cells, and it may be involved in the development of CAD. Genetic polymorphisms in functional regions of the IL17A gene have a plausible role in modulating the risk of CAD.

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