Stem cell differentiation

Genetic expression and functional characterization of the RUNX2 gene in human adult bone marrow mesenchymal stem cells

J. Y. Zhang and Li, L. C., Genetic expression and functional characterization of the RUNX2 gene in human adult bone marrow mesenchymal stem cells, vol. 14, pp. 18210-18217, 2015.

Past studies have revealed the critical role of runt-related transcription factor 2 (RUNX2) in the proliferation and differentiation of mesenchymal stem cells (MSCs). This study therefore aimed to investigate the expression profile of the RUNX2 gene in human bone marrow MSCs and its biological characteristics. Bone marrow MSCs were separated from 12 patients who had received hip joint replacement surgery.

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