susceptibility

Association between RAGE gene polymorphisms and ulcerative colitis susceptibility: a case-control study in a Chinese Han population

Z. T. Wang, Wang, L. Y., Wang, L., Cheng, S., Fan, R., Zhou, J., and Zhong, J., Association between RAGE gene polymorphisms and ulcerative colitis susceptibility: a case-control study in a Chinese Han population, vol. 14, pp. 19242-19248, 2015.

Ulcerative colitis (UC) is an immune-related disease with genetic predisposition. The aim of this study was to investigate the association of three polymorphisms in the receptor for advanced glycation end-products (RAGE) gene with UC risk in a Chinese population. This case-control study involved 72 UC patients and 479 age- and gender-matched healthy controls. Genotyping was performed using the polymerase chain reaction-ligase detection reaction method. Data were analyzed using the Haplo.stats program.

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