susceptibility

Association between N-acetyltransferase 2 polymorphisms and pancreatic cancer risk: a meta-analysis

J. X. Liang, Gao, W., Liang, Y., and Zhou, X. M., Association between N-acetyltransferase 2 polymorphisms and pancreatic cancer risk: a meta-analysis, vol. 14, pp. 17219-17227, 2015.

N-acetyltransferase 2 (NAT2) is an essential phase II enzyme in the metabolism of aromatic and heterocyclic amines and of hydrazines. NAT2 activity can be divided into three phenotypes: rapid, intermediate, and slow. Studies identifying an association between NAT2 polymorphism and the risk of pancreatic cancer have shown conflicting results.

Subscribe to susceptibility