Systemic lupus erythematosus

Analysis of interleukin 19 serum levels and single nucleotide polymorphisms in systemic lupus erythematosus

J. R. Lin, Qin, H. H., Wang, Y., Liang, J., Xu, J. H., Lin, J. R., Qin, H. H., Wang, Y., Liang, J., and Xu, J. H., “Analysis of interleukin 19 serum levels and single nucleotide polymorphisms in systemic lupus erythematosus”, vol. 15, p. -, 2016.

Systemic lupus erythematosus (SLE) is an autoimmune connective tissue disease that affects multiple organs and diminishes a patients’ quality of life. It has been suggested that interleukin 19 (IL-19) is engaged in intercellular signal transduction, which is related to the immune response and the local inflammatory reaction. Single nucleotide polymorphisms (SNPs) have been used to explore the genetic basis underlying the pathogenesis of SLE. In this study, we investigated the potential correlation between the functional IL19 SNP rs2243188 and SLE.

Balance between inflammatory and regulatory cytokines in systemic lupus erythematosus

Y. Yao, Wang, J. B., Xin, M. M., Li, H., Liu, B., Wang, L. L., Wang, L. Q., Zhao, L., Yao, Y., Wang, J. B., Xin, M. M., Li, H., Liu, B., Wang, L. L., Wang, L. Q., and Zhao, L., “Balance between inflammatory and regulatory cytokines in systemic lupus erythematosus”, vol. 15, p. -, 2016.

To investigate the cytokine profile in serum and cerebrospinal fluid (CSF) from patients with systemic lupus erythematosus (SLE) and central nervous system infection, we measured interferon-g (IFN-g), interleukin-1b (IL-1b), IL-4, IL-6, IL-8, IL-10, and IL-17 levels in serum and CSF from 50 SLE patients and 38 matched controls.

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