T1-T2

Gene expression profile and enrichment pathways in different stages of bladder cancer

Z. - Q. Fang, Zang, W. - D., Chen, R., Ye, B. - W., Wang, X. - W., Yi, S. - H., Chen, W., He, F., and Ye, G., Gene expression profile and enrichment pathways in different stages of bladder cancer, vol. 12, pp. 1479-1489, 2013.

Bladder cancer is a highly heterogeneous neoplasm. We examined the gene expression profile in 3 bladder cancer stages (Ta, T1, T2) using expression microarray analysis of 40 bladder tumors. Differentially expressed genes were found by the t-test, with ANXA5, ATP6V1B2, CTGF, GEM, IL13RA1, and LCP1); 5 genes were up-regulated at the Ta-T1 stage, but down-regulated at the T1-T2 stage (ACPP, GNL1, RIPK1, RAPGEF3, and ZER1).

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