TGF-β

Role of PPARα in down-regulating AGE-induced TGF-β and MMP-9 expressions in chondrocytes

J. Wang, Wang, G., Sun, G. W., Wang, J., Wang, G., and Sun, G. W., Role of PPARα in down-regulating AGE-induced TGF-β and MMP-9 expressions in chondrocytes, vol. 15, p. -, 2016.

Peroxisome proliferator-activated receptor is closely associated with the pathogenesis of osteoarthritis. The level of exogenous advanced glycation end-products (AGEs) in articular cartilage is highly associated with the severity of osteoarthritic lesions. However, their interactions and role in promoting osteoarthritisprogression remain unclear.

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