Role of PPARα in down-regulating AGE-induced TGF-β and MMP-9 expressions in chondrocytes
“Role of PPARα in down-regulating AGE-induced TGF-β and MMP-9 expressions in chondrocytes”, vol. 15, p. -, 2016.
, Peroxisome proliferator-activated receptor is closely associated with the pathogenesis of osteoarthritis. The level of exogenous advanced glycation end-products (AGEs) in articular cartilage is highly associated with the severity of osteoarthritic lesions. However, their interactions and role in promoting osteoarthritisprogression remain unclear.