Thiamine

A potential protective role for thiamine in glucose-driven oxidative stress

B. Palabiyik, F. Ghods, J., and E. Ucar, O., A potential protective role for thiamine in glucose-driven oxidative stress, vol. 13, pp. 5582-5593, 2014.

The relationship between glucose repression and the oxidative stress response was investigated in Schizosaccharomyces pombe wild type cells (972h-) and glucose repression resistant mutant type cells (ird11). We aimed to reveal the mechanism of simultaneous resistance to glucose repression and oxidative stress in ird11 mutants. Compared to the wild type, the expression of the sty1 gene was not altered in the ird11 mutant under normal growth conditions, but decreased after exposure to H2O2.

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