Thrombosis

Lack of association between potential prothrombotic genetic risk factors and arterial and venous thrombosis

F. C. G. Evangelista, Rios, D. R. A., Ribeiro, D. D., Carvalho, M. G., Dusse, L. M. S., Fernandes, A. P., and Sabino, A. P., Lack of association between potential prothrombotic genetic risk factors and arterial and venous thrombosis, vol. 14, pp. 9585-9594, 2015.

Recent studies have shown an association between thrombosis and factor VII (FVII), tissue factor (TF), and angiotensin-converting enzyme (ACE). This suggests that individuals with FVII-402 G/A, FVII-401 G/T, TF+5466 A/G, and ACE-287 insertion/deletion (I/D) polymorphisms present an increased risk of venous thrombosis, heart disease, and ischemic stroke compared with controls. In this study, we investigated the frequencies of these polymorphisms and their association with arterial and venous thrombosis.

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