Molecular cloning and tissue distribution profiles of the chicken R-spondin1 gene
“Molecular cloning and tissue distribution profiles of the chicken R-spondin1 gene”, vol. 14, pp. 3090-3097, 2015.
, Rspo1 belongs to the Rspo family, which is composed of 4 members (Rspo1-4) that share 40 to 60% sequence homology and similar domain organizations, and regulate the WNT signaling pathway via a common mechanism. Rspo1 plays a key role in vertebrate development and is an effective mitogenic factor of gastrointestinal epithelial cells. We report the cloning of chicken Rspo1 and its gene expression distribution among tissues.