TLR-4

Toll-like receptor (TLR)-2/4 expression in retinal ganglion cells in a high-glucose environment and its implications

M. Zhao, Li, C. H., Liu, Y. L., Zhao, M., Li, C. H., Liu, Y. L., Zhao, M., Li, C. H., and Liu, Y. L., Toll-like receptor (TLR)-2/4 expression in retinal ganglion cells in a high-glucose environment and its implications, vol. 15, p. -, 2016.

Diabetic retinopathy (DR), a major complication of diabetes mellitus, is the leading cause of adult blindness. The Toll-like receptor (TLR) family is believed to be involved in the pathogenesis and progression of DR. Here, we investigated the expression profiles of TLR-2 and TLR-4 in retinal ganglion cells (RGCs), in an attempt to elucidate the role of these molecules in the etiology of DR. In vitro cultured RGCs were divided into control and high-glucose groups.

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