Toll-like receptor (TLR)-2/4 expression in retinal ganglion cells in a high-glucose environment and its implications
“Toll-like receptor (TLR)-2/4 expression in retinal ganglion cells in a high-glucose environment and its implications”, vol. 15, p. -, 2016.
, Diabetic retinopathy (DR), a major complication of diabetes mellitus, is the leading cause of adult blindness. The Toll-like receptor (TLR) family is believed to be involved in the pathogenesis and progression of DR. Here, we investigated the expression profiles of TLR-2 and TLR-4 in retinal ganglion cells (RGCs), in an attempt to elucidate the role of these molecules in the etiology of DR. In vitro cultured RGCs were divided into control and high-glucose groups.