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Characterization of a novel CAPN3 transcript generated by alternative splicing in cattle

S. Y. Liu, Jiang, H., Yuan, B., Gao, Y., Dai, L. S., and Zhang, J. B., Characterization of a novel CAPN3 transcript generated by alternative splicing in cattle, vol. 14, pp. 457-463, 2015.

Calpain-3 (CAPN3) is a member of the calpain family of Ca2+-regulated cysteine proteases, which play an important role in sarcomere remodeling and mitochondrial protein turnover, and thus, regulating beef tenderness in cattle. Currently, multiple CAPN3 transcripts have been detected in human, monkey, rat, and rabbit. However, whether this transcript is present in cattle remains unknown. In this study, we identified 2 CAPN3 transcripts in the skeletal muscle individuals of local black cattle from Jilin, China.

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