Transcription factor 7-like 2

Correlation of the TCF7L2 (rs7903146) polymorphism with an enhanced risk of type 2 diabetes mellitus: a meta-analysis

Y. Guan, Yan, L. H., Liu, X. Y., Zhu, X. Y., Wang, S. Z., Chen, L. M., Guan, Y., Yan, L. H., Liu, X. Y., Zhu, X. Y., Wang, S. Z., and Chen, L. M., Correlation of the TCF7L2 (rs7903146) polymorphism with an enhanced risk of type 2 diabetes mellitus: a meta-analysis, vol. 15, p. -, 2016.

Increasing evidence has demonstrated that a transcription factor 7-like 2 (TCF7L2) polymorphism (rs7903146) is significantly associated with type 2 diabetes mellitus (T2DM); however, limited sample size and variance of ethnicity in the studies investigating this association have led to conflicting reports regarding its role. Therefore, a comprehensive meta-analysis was conducted to quantitatively assess the association between the TCF7L2 polymorphism (rs7903146) and T2DM including published case-control studies in global populations.

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