Trophoblastic cells

Expression and significance of the imprinted gene PEG10 in placenta of patients with preeclampsia

X. Y. Liang, Chen, X., Jin, Y. Z., Chen, X. O., and Chen, Q. Z., Expression and significance of the imprinted gene PEG10 in placenta of patients with preeclampsia, vol. 13, pp. 10607-10614, 2014.

The aim of this study was to investigate the expression and significance of the imprinted gene PEG10 (paternally expressed gene 10) in preeclampsia placental tissue. Quantitative real-time reverse transcriptase polymerase chain reaction and immunohistochemistry to evaluate mRNA and protein expression and distribution of PEG10 in placental tissues obtained from 22 preeclampsia patients (8 patients with mild preeclampsia, 14 cases of severe preeclampsia). At the same time, 22 cases of normal pregnant women served as controls.

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