Association of TIRAP (MAL) gene polymorhisms with susceptibility to tuberculosis in a Chinese population
, “Association of TIRAP (MAL) gene polymorhisms with susceptibility to tuberculosis in a Chinese population”, vol. 10, pp. 7-15, 2011.
Toll-interleukin 1 receptor (TIR) domain containing adaptor protein (TIRAP; also known as MAL) is an essential adaptor molecule in Toll-like receptor signaling, involved in activating the innate immune response during infection. Genetic variations in the TIRAP gene may influence human susceptibility to infectious disease. To date, in the Chinese population, a possible predisposition of TIRAP gene variants to tuberculosis has not been reported.
