Type 1 diabetes mellitus

Bioinformatic analysis of endothelial progenitor cells exposed to folic acid in type 1 diabetes mellitus

D. N. Fang, He, X. D., Li, X. H., Jia, H., Li, P. Y., Lu, Q., Quan, Z., and Wang, Q. L., Bioinformatic analysis of endothelial progenitor cells exposed to folic acid in type 1 diabetes mellitus, vol. 13, pp. 1-10, 2014.

We investigated the effects of type 1 diabetes mellitus (T1DM) on endothelial progenitor cells (EPCs) at the molecular level and assessed the therapeutic potential of folic acid (FA) in DM. We downloaded the gene expression profile of the EPCs from T1DM patients before and after treatment with FA and from healthy controls. We identified the differentially expressed genes (DEGs) in the EPCs from T1DM patients before and after a four-week period of FA treatment and compared them with those obtained from the healthy subjects by using limma package in R language.

Subscribe to Type 1 diabetes mellitus