Type 2 diabetes

Association of the rs7903146 and rs12255372 polymorphisms in the TCF7L2 gene with type 2 diabetes in a population from northeastern Brazil

C. M. A. R. Barros, Araújo-Neto, A. P., Lopes, T. R., Barros, M. A. L., Motta, F. J. N., Canalle, R., Nunes, L. C. C., Rey, J. A., Burbano, R. R., Lima-Barros, M. A., Yoshioka, F. K. N., and Pinto, G. R., Association of the rs7903146 and rs12255372 polymorphisms in the TCF7L2 gene with type 2 diabetes in a population from northeastern Brazil, vol. 13, pp. 7889-7898, 2014.

Approximately 200 million people suffer from type 2 diabetes (T2D) worldwide, and the rapid increase in the prevalence of this disease is likely a result of multiple environmental factors, such as increased food intake and decreased physical activity in genetically predisposed individuals. Different population studies have demonstrated a strong association of two polymorphic variations in the TCF7L2 gene, the noncoding single nucleotide polymorphisms (SNPs) rs7903146 (C/T) and rs12255372 (G/T), with T2D.

Effects of rehabilitation management on gastric emptying function in older adults with diabetes

Z. M. Shao, Yao, J. F., Chen, J., Yu, Z. W., Yu, X. F., Zheng, J. J., and Tang, X., Effects of rehabilitation management on gastric emptying function in older adults with diabetes, vol. 13, pp. 9244-9252, 2014.

The relationship between gastric emptying dysfunction and blood glucose concentration in elderly with type 2 diabetes mellitus was investigated, and the effect of rehabilitation exercise prescription training on gastric emptying in the geriatric diabetic patients was evaluated. A total of 160 older type 2 diabetic adults and 30 cases of non-diabetic patients were studied with regard to the gastric half emptying time (GET1/2) of solid meals radiolabelled with 99mTc.

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